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Article

E-selectin S128R polymorphism leads to severe asthma.

Iranian journal of allergy, asthma, and immunology - 1 Jun 2007

Nadi Ebrahim, Hajilooi Mehrdad, Zeraati Fatemeh, Ansari Mostafa, Tavana Sasan, Hashemi Sayed Hamid, Rafiei Alireza

Abstract excerpt

The E-selectin mediates the interaction of activated endothelial cells with leukocytes and plays a fundamental role in the pathogenesis of asthma. It has been suggested that an S/R (Serine128Arginine) polymorphism of E-selectin alters ligand binding function. Our purpose in this study was to determine whether this Serine128Arginine polymorphism influences the risk of asthma and also to analyze the possible...

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PMID: 17563404

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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