Article
E-selectin polymorphism in erythema nodosum secondary to sarcoidosis.
Clinical and experimental rheumatology - 1 Jan 2000
Amoli M M, Llorca J, Gomez-Gigirey A, Garcia-Porrua C, Lueiro M, El-Magadmi M, Fernandez M L, Ollier W E R, Gonzalez-Gay M A
Abstract excerpt
OBJECTIVE: E-selectin is expressed on cytokine-stimulated endothelial cells and plays an important role in leukocyte-endothelium interactions and inflammatory cell recruitment. An A/C polymorphism at position +561 in the E-selectin gene, which yields an amino acid exchange from serine to arginine at position 128 in the epidermal growth factor-like domain, has been described. We have assessed whether this...
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