Article
Mutation of the epidermal growth factor receptor gene in the development of adenocarcinoma of the lung.
Lung cancer (Amsterdam, Netherlands) - 1 Oct 2007
Kozuki Toshiyuki, Hisamoto Akiko, Tabata Masahiro, Takigawa Nagio, Kiura Katsuyuki, Segawa Yoshihiko, Nakata Masao, Mandai Koichi, Eguchi Kenji, Ueoka Hiroshi, Tanimoto Mitsune
Abstract excerpt
Recently, a mutation of the epidermal growth factor receptor (EGFR) gene has been reported to be implicated in the development of pulmonary adenocarcinoma. However, the involvement of the mutation in atypical adenomatous hyperplasia (AAH) and multiple adenocarcinomas still remains unclear. We herein examined the EGFR mutations in 9 AAH and 31 adenocarcinoma lesions obtained from 30 Japanese patients. Nine...
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