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Epitope discovery in West Nile virus infection: Identification and immune recognition of viral epitopes

25 Feb 2008

Abstract excerpt

Cytotoxic T lymphocytes (CTL) play an important role in the control and elimination of infection by West Nile virus (WNV), yet the class I human leukocyte antigen (HLA)-presented peptide epitopes that enable CTL recognition of WNV-infected cells remain uncharacterized. The goals of this work were first to discover the peptide epitopes that distinguish the class I HLA of WNV-infected cells and then to test the T...

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PMID: 18299564
DOI: 10.1073/pnas.0711874105

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