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Article

Cardiac Genetic Predisposition in Sudden Infant Death Syndrome.

Journal of the American College of Cardiology - 20 Mar 2018

Tester David J, Wong Leonie C H, Chanana Pritha, Jaye Amie, Evans Jared M, FitzPatrick David R, Evans Margaret J, Fleming Peter, Jeffrey Iona, Cohen Marta C, Tfelt-Hansen Jacob, Simpson Michael A, Behr Elijah R, Ackerman Michael J

Abstract excerpt

BACKGROUND: Sudden infant death syndrome (SIDS) is a leading cause of postneonatal mortality. Genetic heart diseases (GHDs) underlie some cases of SIDS. OBJECTIVES: This study aimed to determine the spectrum and prevalence of GHD-associated mutations as a potential monogenic basis for SIDS. METHODS: A cohort of 419 unrelated SIDS cases (257 male; average age 2.7 ± 1.9 months) underwent whole exome sequencing and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 29544605
DOI: 10.1016/j.jacc.2018.01.030

Genes

KCNH2
KCNQ1
RYR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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