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Article

Allelic penetrance approach as a tool to model two-locus interaction in complex binary traits.

Heredity - 1 Aug 2007

Sepúlveda N, Paulino C D, Carneiro J, Penha-Gonçalves C

Abstract excerpt

Many binary phenotypes do not follow a classical Mendelian inheritance pattern. Interaction between genetic and environmental factors is thought to contribute to the incomplete penetrance phenomena often observed in these complex binary traits. Several two-locus models for penetrance have been proposed to aid the genetic dissection of binary traits. Such models assume linear genetic effects of both loci in...

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PMID: 17551528
DOI: 10.1038/sj.hdy.6800979

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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