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Article

Induction of Bystander Response in Human Glioma Cells using High-Energy Electrons: A Role for TGF-β1

17 Mar 2010

Abstract excerpt

We examined bystander cell death produced in T98G cells by exposure to irradiated cell conditioned medium (ICCM) produced by high-energy 20 MeV electrons at a dose rate of 10 Gy min(-1) and doses up to 20 Gy. ICCM induced a bystander response in T98G glioma cells, reducing recipient cell survival by more than 25% below controls at 5 and 10 Gy. Higher doses increased survival to near control levels. ICCM was...

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PMID: 20518656
DOI: 10.1667/rr1895.1

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