Article
Inferring the timescale of dengue virus evolution under realistic models of DNA substitution.
Journal of molecular evolution - 1 Jun 2007
Dunham Eleca J, Holmes Edward C
Abstract excerpt
Dengue virus (DENV) is the agent of the most widespread vector-borne viral disease of humans. To infer the timescale of DENV evolution with as much accuracy as possible, we compared, within a Bayesian Markov Chain Monte Carlo (MCMC) framework, estimates of phylogenetic tree length using both covarion and noncovarion models of molecular evolution, the latter also incorporating lineage-specific rate variation...
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