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Article

Comparative study of circadian variation in numbers of peripheral blood cells among mouse strains: unique feature of C3H/HeN mice.

Biological & pharmaceutical bulletin - 1 Jun 2007

Ohkura Naoki, Oishi Katsutaka, Sekine Yuji, Atsumi Gen-ichi, Ishida Norio, Matsuda Juzo, Horie Shuichi

Abstract excerpt

We examined strain differences in numbers of blood cells and their circadian rhythms in male Jcl:ICR, BALB/cA, C57BL/6J and C3H/HeN mice. The total numbers of circulating white blood cells (WBCs) were increased during subjective day and night, and the peaks in the active period were common to all strains. However, the number of WBCs in C3H/HeN mice remained lower and plasma levels of corticosterone (CS) were...

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PMID: 17541178
DOI: 10.1248/bpb.30.1177

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