Article
Genotype-specific environmental impact on the variance of blood values in inbred and F1 hybrid mice.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Feb 2006
Klempt Martina, Rathkolb Birgit, Fuchs Edith, de Angelis Martin Hrabé, Wolf Eckhard, Aigner Bernhard
Abstract excerpt
Mice are important models for biomedical research because of the possibility of standardizing genetic background and environmental conditions, which both affect phenotypic variability. Inbred mouse strains as well as F1 hybrid mice are routinely used as genetically defined animal models; however, only a few studies investigated the variance of phenotypic parameters in inbred versus F1 hybrid mice and the...
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