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Article

Correlation of Induction of ATP Binding Cassette Transporter A5 (ABCA5) and ABCB1 mRNAs with Differentiation State of Human Colon Tumor

1 Jan 2007

Abstract excerpt

The ATP binding cassette transporter subtype A5 (ABCA5)-like transporters ABCA5, ABCA6, ABCA8, ABCA9 and ABCA10 form a unique gene cluster within the ABC transporter superfamily, though their function is still poorly understood. The purpose of this study is to examine whether ABCA5-like transporters may play a role in tumor development by measuring their mRNA levels in human tissues and tumors. Intense mRNA...

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PMID: 17541169
DOI: 10.1248/bpb.30.1144

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