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Article

The S447X polymorphism of lipoprotein lipase: effect on the incidence of premature coronary disease and on plasma lipids.

Arquivos brasileiros de cardiologia - 1 Mar 2007

Almeida Kátia A, Strunz Célia M C, Maranhão Raul C, Mansur Antonio P

Abstract excerpt

OBJECTIVE: The objective of this study was to evaluate the effect of polymorphism S447X on plasma lipids of patients with premature coronary artery disease (CAD). METHODS: Plasma lipids and genotypes were determined in 2 groups: 313 patients with premature CAD (<55 years of age) and 150 controls...

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Source

Identifiers

PMID: 17533471
DOI: 10.1590/s0066-782x2007000300008

Genes

CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17533471-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

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Click a neighbor to travelStep 1 · 12 closest

The S447X polymorphism of lipoprotein lipase: effect on the incidence of premature coronary disease and on plasma lipids.PMID 17533471Read ↗

The S447X variant of lipoprotein lipase gene is inversely associated with severity of coronary artery disease.Semantic proximity Read ↗

The association of the S447X mutation in LPL with Coronary artery disease: a meta-analysis.Semantic proximity Read ↗

Lipoprotein lipase D9N, N291S and S447X polymorphisms: their influence on premature coronary heart disease and plasma lipids.Semantic proximity Read ↗

A common truncation variant of lipoprotein lipase (Ser447X) confers protection against coronary heart disease: the Framingham Offspring Study.Semantic proximity Read ↗

S447X variant of the lipoprotein lipase gene, lipids, and risk of coronary heart disease in 3 prospective cohort studies.Semantic proximity Read ↗

The association of APOC4 polymorphisms with premature coronary artery disease in a Chinese Han population.Semantic proximity Read ↗

S447X polymorphism in the lipoprotein lipase gene and the adiponectin level in the general population: results from the Mima study.Semantic proximity Read ↗

Cholesteryl ester transfer protein gene polymorphism (I405V) and premature coronary artery disease in an Iranian population.Semantic proximity Read ↗

The S447X variant of lipoprotein lipase gene is associated with metabolic syndrome and lipid levels among Turks.Semantic proximity Read ↗

LRP1 gene polymorphisms are associated with premature risk of cardiovascular disease in patients with familial hypercholesterolemia.Semantic proximity Read ↗

Association of two genetic variations of lipoprotein lipase, S447X and Hind III, with coronary artery disease and hypertriglyceridemia.Semantic proximity Read ↗

The LPL S447X cSNP is associated with decreased blood pressure and plasma triglycerides, and reduced risk of coronary artery disease.Semantic proximity Read ↗

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