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Article

LRP1 gene polymorphisms are associated with premature risk of cardiovascular disease in patients with familial hypercholesterolemia.

Revista espanola de cardiologia (English ed.) - 1 Sept 2012

Aledo Rosa, Alonso Rodrigo, Mata Pedro, Llorente-Cortés Vicenta, Padró Teresa, Badimon Lina

Abstract excerpt

INTRODUCTION AND OBJECTIVES: LRP1 gene overexpression in atherosclerotic plaque is associated with increased lipid uptake through the vascular wall. The aim of the study was to analyze whether LRP1 modulates the genetic risk of developing premature cardiovascular disease in familial hypercholesterolemia, using single nucleotide polymorphism association analysis. METHODS: Ten polymorphisms of the LRP1 gene...

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Source

Identifiers

PMID: 22819221
DOI: 10.1016/j.recesp.2012.03.013

Genes

LRP1

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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