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Article

Differential sensitivity to interferon influences the replication and transcription of Urabe AM9 mumps virus variants in nerve cells.

Microbes and infection - 1 Jun 2007

Rosas-Murrieta Nora, Herrera-Camacho Irma, Vallejo-Ruiz Verónica, Millán-Pérez-Peña Lourdes, Cruz Carlos, Tapia-Ramírez José, Santos-López Gerardo, Reyes-Leyva Julio

Abstract excerpt

Urabe AM9 mumps virus vaccine causes post-vaccination meningitis. Two variants of Urabe AM9 virus differ in their replication efficiency in human nerve cells, HN-A(1081) variant being more neurotropic than HN-G(1081). The effect of interferon (IFN) on viral replication and transcription was analyzed. Priming of nerve cells with IFN reduced more significantly the replication of HN-G(1081) variant (from 10(2.5) to...

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PMID: 17533145
DOI: 10.1016/j.micinf.2007.03.005

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STAT1
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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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