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Article

Correlation of genetic variability with safety of mumps vaccine Urabe AM9 strain.

Virology - 15 Aug 2001

Amexis G, Fineschi N, Chumakov K

Abstract excerpt

The Urabe AM9 strain of mumps vaccine live is known for its genetic instability and some vaccines derived from this strain were withdrawn from the market due to an excessive number of vaccine-associated parotitis and meningitis cases. To identify the molecular basis of this instability, we determined complete nucleotide sequences of several stocks of the Urabe strain used for vaccine production by different...

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Identifiers

PMID: 11504558
DOI: 10.1006/viro.2001.1009

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