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Article

Transient ligand docking sites in Cerebratulus lacteus mini-hemoglobin.

Gene - 15 Aug 2007

Deng Pengchi, Nienhaus Karin, Palladino Pasquale, Olson John S, Blouin George, Moens Luc, Dewilde Sylvia, Geuens Eva, Nienhaus G Ulrich

Abstract excerpt

The monomeric hemoglobin of the nemertean worm Cerebratulus lacteus functions as an oxygen storage protein to maintain neural activity under hypoxic conditions. It shares a large, apolar matrix tunnel with other small hemoglobins, which has been implicated as a potential ligand migration pathway. Here we explore ligand migration and binding within the distal heme pocket, to which the tunnel provides access to...

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Share to Carbon Monoxide
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17531406
DOI: 10.1016/j.gene.2007.01.037
PMCID: PMC1986801

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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