Article
Role of local structure and dynamics of small ligand migration in proteins: a study of a mutated truncated hemoprotein from Thermobifida fusca by time resolved MIR spectroscopy.
The journal of physical chemistry. B - 7 Aug 2014
Patrizi Barbara, Lapini Andrea, Di Donato Mariangela, Marcelli Agnese, Lima Manuela, Righini Roberto, Foggi Paolo, Baiocco Paola, Bonamore Alessandra, Boffi Alberto
Abstract excerpt
Carbon monoxide recombination dynamics in a mutant of the truncated hemoglobin from Thermobida fusca (3F-Tf-trHb) has been analyzed by means of ultrafast Visible-pump/MidIR-probe spectroscopy and compared with that of the wild-type protein. In 3F-Tf-trHb, three topologically relevant amino acids, responsible for the ligand stabilization through the formation of a H-bond network (TyrB10 TyrCD1 and TrpG8), have...
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