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Article

Quantitative assessment of CYP2D6 polymorphisms and risk of Alzheimer's disease: a meta-analysis.

Journal of the neurological sciences - 15 Aug 2014

Lu Yu, Qin Xue, Li Shan, Zhang Xiaolian, He Yu, Peng Qiliu, Deng Yan, Wang Jian, Xie Li, Li Taijie, Zeng Zhiyu

Abstract excerpt

BACKGROUND: CYP2D6 gene encoding CYP2D6 enzyme belonging to the cytochrome P450 system has aroused long attention being a candidate gene for Alzheimer's disease (AD), but the results remain inconsistent and underpowered. OBJECTIVES: To investigate the contradictory results, the effect of single CYP2D6 polymorphism- CYP2D6*4, together with CYP2D6 phenotypes on the risk of AD, was evaluated using a meta-analysis....

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Identifiers

PMID: 24909950
DOI: 10.1016/j.jns.2014.05.033

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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