Article
Adaptation of Borna disease virus to new host species attributed to altered regulation of viral polymerase activity.
Journal of virology - 1 Aug 2007
Ackermann Andreas, Staeheli Peter, Schneider Urs
Abstract excerpt
Borna disease virus (BDV) can persistently infect the central nervous system of a broad range of mammalian species. Mice are resistant to infections with primary BDV isolates, but certain laboratory strains can be adapted to replicate in mice. We determined the molecular basis of adaptation by st...
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