Article
Widespread pyocyanin over-production among isolates of a cystic fibrosis epidemic strain.
BMC microbiology - 23 May 2007
Fothergill Joanne L, Panagea Stavroula, Hart Charles A, Walshaw Martin J, Pitt Tyrone L, Winstanley Craig
Abstract excerpt
BACKGROUND: Some isolates of the Liverpool cystic fibrosis epidemic strain of Pseudomonas aeruginosa exhibit an unusual virulence-related phenotype, characterized by over-production of quorum sensing-regulated exoproducts such as pyocyanin and LasA protease. Our aim was to determine the prevalence of this unusual phenotype amongst isolates of the epidemic strain, and to study other intraclonal phenotypic and...
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