Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A large-scale mutagenesis screen to identify seizure-resistant zebrafish.

Epilepsia - 1 Jun 2007

Baraban Scott C, Dinday Matthew T, Castro Peter A, Chege Sally, Guyenet Stephan, Taylor Michael R

Abstract excerpt

PURPOSE: Zebrafish are a vertebrate organism ideally suited to mutagenesis screening strategies. Although a genetic basis for seizure susceptibility and epilepsy is well established, no efforts have been made to study seizure resistance. Here we describe a novel strategy to isolate seizure-resistant zebrafish mutants from a large-scale mutagenesis screen. METHODS: Seizures were induced with pentylenetetrazole...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Behavior, Animal
Share to Larva
Share to Locomotion

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Pentylenetetrazole

Share to Seizures

Share to Status Epilepticus

Share to Superior Colliculi

Share to Zebrafish

Source

Open in PubMed Open full text

Identifiers

PMID: 17521353
DOI: 10.1111/j.1528-1167.2007.01075.x
PMCID: PMC2211740

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A large-scale mutagenesis screen to identify seizure-resistant zebrafish.PMID 17521353Read ↗

Advancing epilepsy treatment through personalized genetic zebrafish models.Semantic proximity Read ↗

Zebrafish as a model for studying genetic aspects of epilepsy.Semantic proximity Read ↗

Phenotypic analysis of catastrophic childhood epilepsy genes: The Epilepsy Zebrafish ProjectSemantic proximity Read ↗

Building a zebrafish toolkit for investigating the pathobiology of epilepsy and identifying new treatments for epileptic seizures.Semantic proximity Read ↗

Clemizole and Trazodone are Effective Antiseizure Treatments in a Zebrafish Model of STXBP1 DisorderSemantic proximity Read ↗

Phenotypic analysis of catastrophic childhood epilepsy genes.Semantic proximity Read ↗

Testing of putative antiseizure drugs in a preclinical Dravet syndrome zebrafish modelSemantic proximity Read ↗

A Zebrafish Platform to Model Human <i>SCN2A</i> and <i>SCN8A</i> Epilepsy and Evaluate Anti-Seizure MedicationsSemantic proximity Read ↗

Zebrafish as an Innovative Tool for Epilepsy Modeling: State of the Art and Potential Future DirectionsSemantic proximity Read ↗

Zebrafish models of candidate human epilepsy-associated genes provide evidence of hyperexcitabilitySemantic proximity Read ↗

Modeling seizure-related behavioral and endocrine phenotypes in adult zebrafish.Semantic proximity Read ↗

A Zebrafish-Based Platform for High-Throughput Epilepsy Modeling and Drug Screening in F0.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.