Article
Increased expression of ampC in Pseudomonas aeruginosa mutants selected with ciprofloxacin.
Antimicrobial agents and chemotherapy - 1 Aug 2007
Wolter Daniel J, Schmidtke Amber J, Hanson Nancy D, Lister Philip D
Abstract excerpt
Two Pseudomonas aeruginosa mutants exhibiting increased expression of ampC were selected during exposure to ciprofloxacin. These mutants also exhibited significant increases in mexCD-oprJ expression, but further studies failed to show a link between the increased expression of mexCD-oprJ and ampC. Increased ampC expression was not related to mutations within ampR, the ampC-ampR intergenic region, ampD, ampDh2, or...
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