Article
Actin cytoskeleton as a putative target of the neem limonoid Azadirachtin A.
Insect biochemistry and molecular biology - 1 Jun 2007
Anuradha Aritakula, Annadurai Ramaswamy S, Shashidhara L S
Abstract excerpt
Limonoids isolated from the Indian neem tree (Azadirachta indica) have been gaining global acceptance in agricultural applications and in contemporary medicine for their myriad but discrete properties. However, their mode of action is still not very well understood. We have studied the mode of action of Azadirachtin A, the major limonoid of neem seed extracts, using Drosophila melanogaster as the model system....
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