Article
Plant coumarins enhance viral pathogenicity by miRNA-mediated apoptosis in insect herbivores
2025-10-02
Abstract excerpt
<h4>SUMMARY</h4> Plant secondary metabolites (PSM) influence the susceptibility of insect herbivores to entomoviruses, but the apoptosis mechanism is not clear. Among plant hosts screened, the level of coumarin is correlated with NPV-mediated mortality, with high coumarin levels associated with high mortality and low coumarin levels with low mortality. Flow cytometry and morphological experiments showed that coum...
Topics
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- Aquaculture disease management and microbiota
- Autophagy in Disease and Therapy
- Cell death mechanisms and regulation
- Insect-Plant Interactions and Control
- Mosquito-borne diseases and control
- Plant Virus Research Studies
- Ubiquitin and proteasome pathways
- Viral Infectious Diseases and Gene Expression in Insects
Identifiers and source
- Literature Corpus work
- cef6bda3-6e86-504f-9916-87730b72c0b3
- DOI
- 10.1101/2025.09.29.679223