Article
Role of the extracellular loop in the folding of a CFTR transmembrane helical hairpin.
Biochemistry - 19 Jun 2007
Wehbi Hania, Rath Arianna, Glibowicka Mira, Deber Charles M
Abstract excerpt
The folding of membrane-spanning domains into their native functional forms depends on interactions between transmembrane (TM) helices joined by covalent loops. However, the importance of these covalent linker regions in mediating the strength of helix-helix associations has not been systematical...
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