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Embryo development after successful somatic cell nuclear transfer to in vitro matured human germinal vesicle oocytes

19 May 2007

Abstract excerpt

BACKGROUND: Somatic cell nuclear transfer (SCNT) involves the transfer of somatic cell nuclei into enucleated oocytes. Because human in vivo matured oocytes are scarcely available, we investigated whether in vitro matured (IVM) germinal vesicle (GV) oocytes could also support preimplantation development of human cloned embryos. METHODS: Three groups were used for SCNT: in vitro matured GV oocytes (IVM oocytes),...

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PMID: 17513316
DOI: 10.1093/humrep/dem106

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