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Article

Immunogenicity of the outer domain of a HIV-1 clade C gp120.

Retrovirology - 17 May 2007

Chen Hongying, Xu Xiaodong, Jones Ian M

Abstract excerpt

BACKGROUND: The possibility that a sub domain of a C clade HIV-1 gp120 could act as an effective immunogen was investigated. To do this, the outer domain (OD) of gp120CN54 was expressed and characterized in a construct marked by a re-introduced conformational epitope for MAb 2G12. The expressed sequence showed efficient epitope retention on the isolated ODCN54 suggesting authentic folding. To facilitate...

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Identifiers

PMID: 17509143
DOI: 10.1186/1742-4690-4-33
PMCID: PMC1891314

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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