Article
Replication mutations differentially enhance RecA-dependent and RecA-independent recombination between tandem repeats in Bacillus subtilis.
Molecular microbiology - 1 Mar 2001
Bruand C, Bidnenko V, Ehrlich S D
Abstract excerpt
We have studied DNA recombination between 513 bp tandem direct repeats present in a kanamycin resistance gene inserted in the Bacillus subtilis chromosome. Tandem repeat deletion was not significantly affected by a recA mutation. However, recombination was stimulated by mutations in genes encoding replication proteins, including the primosomal proteins DnaB, DnaD and the DnaG primase, the putative DNA polymerase...
Topics
- Bacillus subtilis
- Bacterial Proteins
- DNA Replication
- Gene Deletion
- Gene Expression Regulation, Bacterial
- Kanamycin Resistance
- Mutation
- Rec A Recombinases
- Recombination, Genetic
- Tandem Repeat Sequences