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Article

Coreceptor tropism in human immunodeficiency virus type 1 subtype D: high prevalence of CXCR4 tropism and heterogeneous composition of viral populations.

Journal of virology - 1 Aug 2007

Huang Wei, Eshleman Susan H, Toma Jonathan, Fransen Signe, Stawiski Eric, Paxinos Ellen E, Whitcomb Jeannette M, Young Alicia M, Donnell Deborah, Mmiro Francis, Musoke Philippa, Guay Laura A, Jackson J Brooks, Parkin Neil T, Petropoulos Christos J

Abstract excerpt

In human immunodeficiency virus type 1 (HIV-1) subtype B, CXCR4 coreceptor use ranges from approximately 20% in early infection to approximately 50% in advanced disease. Coreceptor use by non-subtype B HIV is less well characterized. We studied coreceptor tropism of subtype A and D HIV-1 collected from 68 pregnant, antiretroviral drug-naive Ugandan women (HIVNET 012 trial). None of 33 subtype A or 10...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17507467
DOI: 10.1128/JVI.00218-07
PMCID: PMC1951291

Genes

CXCR4
CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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