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Article

Gap junctional proteins of animals: the innexin/pannexin superfamily.

Progress in biophysics and molecular biology - 1 Jan 2000

Yen Ming Ren, Saier Milton H

Abstract excerpt

There has been some controversy as to whether vertebrate pannexins are related to invertebrate innexins. Using statistical, topological and conserved sequence motif analyses, we establish that these proteins belong to a single superfamily. We also demonstrate the occurrence of large homologues with C-terminal proline-rich domains that may have arisen by gene fusion events. Phylogenetic analyses reveal the...

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Identifiers

PMID: 17507077
DOI: 10.1016/j.pbiomolbio.2007.03.006
PMCID: PMC2592087

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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