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Article

JAK-STAT Signaling: From Interferons to Cytokines

15 May 2007

Abstract excerpt

50 years ago Isaacs and Lindenmann (1Isaacs A. Lindenmann J. Proc. R. Soc. Lond. B. Biol. Sci. 1957; 147: 258-267Crossref PubMed Google Scholar) first described interferons (IFNs) 2The abbreviations used are: IFN, interferon; JAK, Janus kinase; STAT, signal transducers and activators of transcription; JH, JAK homology; γC, γ-chain; SH2, Src homology 2; IL, interleukin; IFNAR, IFN-α receptor chain; ISGF,...

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PMID: 17502367
DOI: 10.1074/jbc.r700016200

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