Article
DNA repair gene XPC genotypes/haplotypes and risk of lung cancer in a Chinese population.
International journal of cancer - 20 Jun 2005
Hu Zhibin, Wang Yonggang, Wang Xinru, Liang Gang, Miao Xiaoping, Xu Yaochu, Tan Wen, Wei Qingyi, Lin Dongxin, Shen Hongbing
Abstract excerpt
DNA repair is central to normal cellular functions, and polymorphisms of DNA repair genes may cause variation in DNA repair capacity in the general population. Newly identified polymorphisms of xeroderma pigmentosum group C (XPC), one of the nucleotide excision repair genes, were shown to contribute to genetic susceptibility to cancer. In this study, we hypothesized that 2 exonic variants C499T and A939C and...
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