Article
S1 gene sequence heterogeneity of a pathogenic infectious bronchitis virus strain and its embryo-passaged, attenuated derivatives.
Avian pathology : journal of the W.V.P.A - 1 Jun 2007
Liu Shengwang, Han Zongxi, Chen Jianfei, Liu Xin, Shao Yuhao, Kong Xiangang, Tong Guangzhi, Rong Jungong
Abstract excerpt
Infectious bronchitis virus CK/CH/LDL/97I was attenuated by serial passage in chicken embryos. Virus of passage 115 was attenuated as determined by clinical response to inoculation to 15-day-old specific pathogen free chickens. The vaccination-challenge test showed that the attenuated passage 115 virus could afford protection against the homologous pathogenic virus, passage 5, by the clinical response. Based on...
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