Article
Association study between the fibronectin gene and schizophrenia.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Jan 2003
Nakata Kenji, Ujike Hiroshi, Sakai Ayumu, Takaki Manabu, Imamura Takaki, Tanaka Yuji, Kuroda Shigetoshi
Abstract excerpt
Fibronectin is one of the cell adhesion proteins. Adhesion molecules play an important role in neural and synaptic genesis, and their dysfunction may result in neurodevelopmental abnormalities, which have been assumed to be a factor in the pathogenesis of schizophrenia. To examine the possible involvement of fibronectin in the etiology of schizophrenia, we analyzed six polymorphisms, located in introns 2, 21, 24,...
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