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Article

Essentiality is an emergent property of metabolic network wiring.

FEBS letters - 29 May 2007

Palumbo Maria Concetta, Colosimo Alfredo, Giuliani Alessandro, Farina Lorenzo

Abstract excerpt

The topological bases of essentiality in the yeast metabolic network from the perspective of double mutations are the subject of this study. A strong relationship between essentiality and the 'missing alternative' topological property is shown in terms of the presence of multiple genes synthesizing the same enzyme, supplementary enzymes participating in the same metabolic reaction, and availability of other...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 17493616
DOI: 10.1016/j.febslet.2007.04.067

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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