Article
AI-2-dependent gene regulation in Staphylococcus epidermidis.
BMC microbiology - 8 Jan 2008
Li Min, Villaruz Amer E, Vadyvaloo Viveka, Sturdevant Daniel E, Otto Michael
Abstract excerpt
BACKGROUND: Autoinducer 2 (AI-2), a widespread by-product of the LuxS-catalyzed S-ribosylhomocysteine cleavage reaction in the activated methyl cycle, has been suggested to serve as an intra- and interspecies signaling molecule, but in many bacteria AI-2 control of gene expression is not completely understood. Particularly, we have a lack of knowledge about AI-2 signaling in the important human pathogens...
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