Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The VHL tumor suppressor inhibits expression of the IGF1R and its loss induces IGF1R upregulation in human clear cell renal carcinoma

7 May 2007

Abstract excerpt

No abstract is available from the source.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adrenal and Paraganglionic Tumors
Share to Cancer, Hypoxia, and Metabolism
Share to Growth Hormone and Insulin-like Growth Factors

Source

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Identifiers

PMID: 17486080
DOI: 10.1038/sj.onc.1210474

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The VHL tumor suppressor inhibits expression of the IGF1R and its loss induces IGF1R upregulation in human clear cell renal carcinomaPMID 17486080Read ↗

High VHL Expression Reverses Warburg Phenotype and Enhances Immunogenicity in Kidney Tumor Cells.Semantic proximity Read ↗

Mutational status of VHL gene and its clinical importance in renal clear cell carcinoma.Semantic proximity Read ↗

Mutations in tumor suppressor genes Vhl and Rassf1a cause DNA damage, chromosomal instability and induce gene expression changes characteristic of clear cell renal cell carcinomaSemantic proximity Read ↗

Investigation of VHL gene associated with miR-223 in clear cell renal cell carcinoma.Semantic proximity Read ↗

ZBRK1, a novel tumor suppressor, activates VHL gene transcription through formation of a complex with VHL and p300 in renal cancerSemantic proximity Read ↗

Inactivation of the PBRM1 tumor suppressor gene amplifies the HIF-response in VHL <sup>−/−</sup> clear cell renal carcinomaSemantic proximity Read ↗

Requirement for the von Hippel-Lindau tumor suppressor gene for functional epidermal growth factor receptor blockade by monoclonal antibody C225 in renal cell carcinoma.Semantic proximity Read ↗

VHL tumor suppressor gene alterations associated with good prognosis in sporadic clear-cell renal carcinoma.Semantic proximity Read ↗

Implication of VHL, ERK5, and HIF-1alpha in clear cell renal cell carcinoma: Molecular basis.Semantic proximity Read ↗

Alterations in VHL as potential biomarkers in renal-cell carcinomaSemantic proximity Read ↗

von Hippel-Lindau gene status and response to vascular endothelial growth factor targeted therapy for metastatic clear cell renal cell carcinoma.Semantic proximity Read ↗

VHL gene mutations in renal cell carcinoma: role as a biomarker of disease outcome and drug efficacy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.