Article
Association between the calcitonin-related peptide alpha (CALCA) gene and essential hypertension in Japanese subjects.
American journal of hypertension - 1 May 2007
Morita Akihiko, Nakayama Tomohiro, Soma Masayoshi, Mizutani Tomohiko
Abstract excerpt
BACKGROUND: Calcitonin-related peptide alpha (CALCA) is a neuropeptide that is a very potent vasodilator. It has been reported that CALCA knockout mice have a significantly elevated systolic blood pressure (BP). The aims of this study were to discover novel polymorphisms or mutations in the 5' flanking region of the human CALCA gene in Japanese subjects and to assess the association between this gene and...
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