Article
Association study of calcitonin gene-related polypeptide-alpha (CALCA) gene polymorphism with migraine.
Brain research - 10 Mar 2011
Menon S, Buteri J, Roy B, Murrell M, Quinlan S, Macmillan J C, Lea R A, Haupt L M, Griffiths L R
Abstract excerpt
Migraine is a neurological disorder that is associated with increased levels of calcitonin gene-related peptide (CGRP) in plasma. CGRP, being one of the mediators of neurogenic inflammation and a phenomenon implicated in the pathogenesis of migraine headache, is thus suggested to have an important role in migraine pathophysiology. Polymorphisms of the CALCA gene have been linked to Parkinson's disease, ovarian...
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