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Article

Codon Y791F mutations in a large kindred: is prophylactic thyroidectomy always indicated?

World journal of surgery - 1 May 2007

Vestergaard Peter, Vestergaard Else Marie, Brockstedt Helle, Christiansen Peer

Abstract excerpt

BACKGROUND: RET proto-oncogene mutations are associated with medullary thyroid carcinomas usually requiring preventive thyroidectomy in gene carriers. We present a large kindred with the Y791F mutation in the RET proto-oncogene that did not have medullary thyroid carcinomas. PATIENTS AND METHODS: Eight members of a Danish family with the Y791F mutation participated. All gene carriers underwent pentagastrin...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17483988
DOI: 10.1007/s00268-006-0446-1

Genes

RET

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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