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Article

A laminin-collagen complex drives human epidermal carcinogenesis through phosphoinositol-3-kinase activation.

Cancer research - 1 May 2007

Waterman Elizabeth A, Sakai Noriyasu, Nguyen Ngon T, Horst Basil A J, Veitch Dallas P, Dey Clara N, Ortiz-Urda Susana, Khavari Paul A, Marinkovich M Peter

Abstract excerpt

Laminin-332 (formerly laminin-5) and collagen VII are basement membrane proteins expressed at the invasive front of human squamous cell carcinoma (SCC) tumors. These proteins have protumorigenic properties, but whether laminin-332 and collagen VII promote SCC tumors by providing adhesion or other nonadhesive extracellular cues, or whether laminin-332 and collagen VII interact together in this process remains...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17483338
DOI: 10.1158/0008-5472.CAN-06-4141

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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A laminin-collagen complex drives human epidermal carcinogenesis through phosphoinositol-3-kinase activation.PMID 17483338Read ↗

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