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Article

AlphaPS2 integrin-mediated muscle attachment in Drosophila requires the ECM protein Thrombospondin.

Mechanisms of development - 1 Jul 2007

Chanana Bhavna, Graf Roland, Koledachkina Tatyana, Pflanz Ralf, Vorbrüggen Gerd

Abstract excerpt

During Drosophila embryogenesis, the attachment of somatic muscles to epidermal tendon cells requires heterodimeric PS-integrin proteins (alpha- and beta-subunits). The alpha-subunits are expressed complementarily, either tendon cell- or muscle-specific, whereas the beta-integrin subunit is expressed in both tissues. Mutations of beta-integrin cause a severe muscle detachment phenotype, whereas alpha-subunit...

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Identifiers

PMID: 17482800
DOI: 10.1016/j.mod.2007.03.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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