Article
Functional polymorphisms of JWA gene are associated with risk of bladder cancer.
Journal of toxicology and environmental health. Part A - 1 Jun 2007
Li Chun-Ping, Zhu Yu-Jie, Chen Rui, Wu Wei, Li Ai-Ping, Liu Jia, Liu Qi-Zhan, Wei Qing-Yi, Zhang Zheng-Dong, Zhou Jian-Wei
Abstract excerpt
The JWA gene is a novel cell differentiation-related gene thought to be a responsive gene in response to DNA damage and repair induced by environmental stressors. Recently, a novel single nucleotide polymorphism (SNP) was identified in the promoter of the JWA gene (-76GC) that may alter the transcription activity and thus play a role in increased risk of bladder cancer. Further, studies were conducted to screen...
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