Article
Single nucleotide polymorphism of the JWA gene is associated with risk of leukemia: a case-control study in a Chinese population.
Journal of toxicology and environmental health. Part A - 1 Jun 2007
Zhu Yu-Jie, Li Chun-Ping, Tang Wei-Yan, Li Ai-Ping, Liu Qi-Zhan, Zhou Jian-Wei
Abstract excerpt
The JWA gene was initially cloned as a novel cell differentiation-associated gene and was subsequently found to be an environmental responsive gene. The JWA gene also produced a marked effect during chemical-induced multidirectional differentiations of primary and human myeloid leukemia cells. Recently, a novel single nucleotide polymorphism (SNP) in exon2 of the JWA gene (454CA) was identified that may play a...
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