Article
CCR2-64I is a risk factor for development of bladder cancer.
Genetics and molecular research : GMR - 13 Apr 2010
Narter K F, Agachan B, Sozen S, Cincin Z B, Isbir T
Abstract excerpt
Chemokines are potent proinflammatory cytokines that are implicated in numerous inflammatory diseases. Proinflammatory gene polymorphisms lead to variations in the production and concentration of inflammatory proteins. We investigated a possible association between polymorphisms in chemokine and chemokine receptor genes (MCP-1 A-2518G and CCR2-V64I) and bladder cancer risk. Genotypes were determined by PCR-RFLP...
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