Article
Assessment of the antioxidant/prooxidant status of murine skin following topical treatment with 12-O-tetradecanoylphorbol-13-acetate and throughout the ontogeny of skin cancer. Part I: Quantitation of superoxide dismutase, catalase, glutathione peroxidase and xanthine oxidase.
Carcinogenesis - 1 Dec 1991
Reiners J J, Thai G, Rupp T, Cantu A R
Abstract excerpt
The activities of several enzymes involved in reactive oxygen production and detoxification were quantified in murine skin during the ontogeny of chemically induced skin cancer. Relative to solvent-treated controls, the specific activities of epidermal superoxide dismutase (SOD), catalase (CAT) a...
Topics
- Administration, Topical
- Animals
- Carcinoma, Squamous Cell
- Catalase
- Female
- Glutathione Peroxidase
- Mice
- Mice, Inbred Strains
- Oxygen
- Papilloma
- Phenotype
- Skin
- Skin Neoplasms
- Superoxide Dismutase
- Tetradecanoylphorbol Acetate