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Article

Evolution of gene overlaps: relative reading frame bias in prokaryotic two-component system genes.

Journal of molecular evolution - 1 Apr 2007

Cock Peter J A, Whitworth David E

Abstract excerpt

During a survey of two-component system genes, a list of neighboring histidine kinase and response regulator genes, encoded on the same strand, was compiled from over 200 fully sequenced bacteria. It was observed that many gene pairs overlapped, and although such overlaps can potentially occur in two phases (relative reading frames), one phase predominated for overlaps of seven or more nucleotides. Preference for...

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Identifiers

PMID: 17479344
DOI: 10.1007/s00239-006-0180-1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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