Article
Re-annotation of genome microbial coding-sequences: finding new genes and inaccurately annotated genes.
BMC bioinformatics - 1 Jan 2002
Bocs Stéphanie, Danchin Antoine, Médigue Claudine
Abstract excerpt
BACKGROUND: Analysis of any newly sequenced bacterial genome starts with the identification of protein-coding genes. Despite the accumulation of multiple complete genome sequences, which provide useful comparisons with close relatives among other organisms during the annotation process, accurate gene prediction remains quite difficult. A major reason for this situation is that genes are tightly packed in...
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