Article
The cell cycle inhibitor p57(Kip2) promotes cell death via the mitochondrial apoptotic pathway.
Cell death and differentiation - 1 Aug 2007
Vlachos P, Nyman U, Hajji N, Joseph B
Abstract excerpt
The p57(Kip2) gene belongs to the Cip/Kip family of cyclin-dependent kinase (CDK) inhibitors and has been suggested to be a tumor suppressor gene, being inactivated in various types of human cancers. However, little is known concerning p57(Kip2) possible interplay with the apoptotic cell death ma...
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