Article
Influence of combined methionine synthase (MTR 2756A > G) and methylenetetrahydrofolate reductase (MTHFR 677C > T) polymorphisms to plasma homocysteine levels in Korean patients with ischemic stroke.
Yonsei medical journal - 30 Apr 2007
Kim Ok Joon, Hong Sun Pyo, Ahn Jung Yong, Hong Seung Ho, Hwang Tae Sun, Kim Soo Ok, Yoo Wangdon, Oh Doyeun, Kim Nam Keun
Abstract excerpt
PURPOSE: Methionine synthase (MTR) and 5,10-methylenetetrahydrofolate reductase (MTHFR) are the main regulatory enzymes for homocysteine metabolism. The present case- control study was conducted to determine whether there is an association between the MTR 2756A > G or MTHFR 677C > T polymorphism and plasma homocysteine concentration in Korean subjects with ischemic stroke. MATERIALS AND METHODS: DNA samples of...
Topics
- 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase
- Aged
- DNA
- Female
- Genotype
- Homocysteine
- Humans
- Male
- Methylenetetrahydrofolate Reductase (NADPH2)
- Middle Aged
- Polymorphism, Single Nucleotide
- Stroke